Tab Montral is a combination anti-allergy medicine that contains montelukast and levocetirizine. It is used to relieve symptoms of allergic rhinitis, such as sneezing, runny or blocked nose, itchy eyes, and watery eyes, and may also be prescribed to help prevent asthma symptoms in some patients. By combining two medicines with different mechanisms of action, Montral provides broader control of allergy symptoms than either medicine alone. Mechanism of Action of Tab Montral Montral works through the combined actions of montelukast and levocetirizine. Montelukast is a leukotriene receptor antagonist. During an allergic reaction, the body releases inflammatory chemicals called leukotrienes, which cause airway narrowing, swelling, increased mucus production, and nasal congestion. Montelukast blocks leukotriene (CysLT1) receptors, preventing these chemicals from producing their effects. This helps reduce airway inflammation, improve breathing in people with asthma, and relieve symptoms of allergic rhinitis, such as nasal congestion. Levocetirizine is a second-generation antihistamine that selectively blocks H1 histamine receptors. Histamine is one of the main chemicals released during an allergic reaction and is responsible for symptoms such as sneezing, itching, watery eyes, and a runny nose. By preventing histamine from binding to its receptors, levocetirizine relieves these symptoms. It also reduces the movement of inflammatory cells involved in the late phase of allergic reactions, helping to control ongoing inflammation. Together, these medicines block two key pathways involved in allergic reactions, providing effective relief from allergy symptoms while helping to reduce inflammation. Montral Uses Montral is used to relieve and prevent symptoms of allergic rhinitis (hay fever) and to help manage asthma in appropriate patients. It combines montelukast and levocetirizine, which work together to reduce inflammation and block the effects of histamine, providing effective relief from allergy symptoms. Montral is Commonly Prescribed For: Tab Montral Dosage The recommended dosage of Montral depends on the patient’s age. Montral is approved for use in adults and adolescents aged 15 years and older, while Montral Kid is intended for children aged 2–5 years under medical supervision taken exactly as prescribed by your healthcare provider.  Tab Montral Side Effects Like all medicines, Montral may cause side effects, although not everyone experiences them. Since Montral contains montelukast and levocetirizine, side effects may occur from either ingredient. Common side effects include: Serious but Rare Side Effects Include: Seek immediate medical attention if you develop swelling of the face or throat, difficulty breathing, severe skin reactions, yellowing of the skin or eyes, or unusual mood or behavioral changes. Contraindications: Who shouldn’t take Montral Although Tab Montral is generally well tolerated, it should not be used in certain situations. Do not take Montral if any of the following apply to you  Montral Price in Nigeria The price of Montral tablets in Nigeria typically ranges from ₦3,000 to ₦4,500, depending on the pharmacy, location, and supplier. Online and retail pharmacy prices may also vary due to stock availability and fluctuations in exchange rates. To ensure you receive a genuine product at a fair price, purchase Montral from licensed pharmacies or reputable online pharmacy platforms. As prices can change over time, it’s a good idea to compare prices at trusted pharmacies before making a purchase. Montral Drug Interactions Montral contains montelukast and levocetirizine, so it may interact with certain medications, alcohol, and substances. Always inform your healthcare provider about all prescription medicines, over-the-counter drugs, herbal products, and supplements you are taking before starting Montral. Montelukast Interactions Montelukast generally has a low potential for drug interactions and can be used alongside many medicines commonly prescribed for asthma. It has not been shown to significantly interact with medications such as theophylline, prednisone, prednisolone, oral contraceptives, digoxin, or warfarin. However, some medicines may reduce the effectiveness of montelukast, including: These medications increase the activity of liver enzymes that break down montelukast, leading to lower levels of the medicine in the body. Levocetirizine Interactions Levocetirizine has few clinically significant drug interactions. However, caution is advised when taking it with: Frequently Asked Questions If you have any questions not answered below, you can reach out to our pharmacist team. What Is the Difference Between Montral 10 mg and Montral 5 mg?  Montral 10 mg and Montral 5 mg (Montral Kid) differ mainly in their montelukast strength and the age groups they are designed for. Montral 10 mg is intended for adults and adolescents, while Montral 5 mg is formulated for children and should only be used according to the recommended pediatric dosing.  Should I take Montral Tablet in the morning or at night?  Montral Tablet is usually taken once daily in the evening, as this is when montelukast is generally most effective for preventing asthma symptoms. However, your healthcare provider may recommend taking it at a time that best controls your symptoms. Always take Montral exactly as prescribed and at the same time each day. Can Montral Tablet Make You Sleepy?  Yes, Montral Tablet can make some people feel sleepy or drowsy. This effect is mainly due to levocetirizine, the antihistamine in Montral. If you experience drowsiness, avoid driving, operating machinery, or performing tasks that require alertness until you know how the medicine affects you.  What Are the Best Substitutes for Montral Tablet? Levkast is an alternative brand to Montral; it also contains the same actives; Montelukast (as sodium) 10mg Levocetirizine dihydrochloride 5mg Sources Emdex Drug Information Nafdac Green Book Medical Disclaimer The information provided on Me & You Pharma is for educational and informational purposes only and is not intended to replace professional medical advice, diagnosis, or treatment. While our content is reviewed for accuracy, it should not be used as a substitute for consultation with a qualified healthcare professional. Always seek the advice of your doctor, pharmacist, or other licensed healthcare provider before starting, stopping, or changing any medication or treatment. Never disregard professional medical advice or delay seeking it because of something you have read on this website.